Transposable elements and the dynamic somatic genome

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Perspective : Transposable Elements , Parasitic Dna , and Genome

The nature of the role played by mobile elements in host genome evolution is reassessed considering numerous recent developments in many areas of biology. It is argued that easy popular appellations such as ‘‘selfish DNA’’ and ‘‘junk DNA’’ may be either inaccurate or misleading and that a more enlightened view of the transposable element-host relationship encompasses a continuum from extreme pa...

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Transposable elements and host genome evolution.

Several recent reports have challenged the idea that transposable elements (TEs) are mainly 'selfish' or 'junk' DNA with little importance for host evolution. It has been proposed that TEs have the potential to provide host genomes with the ability to enhance their own evolution. They might also be a major source of genetic diversity, allowing response to environmental changes. Because the rela...

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Genome Size and the Role of Transposable Elements

The lack of correlation between genome size and organismal complexity was early on dubbed the “C-value Paradox;” it holds even when gene number is considered instead of overall organismal complexity. The sequencing of large eukaryotic genomes has now conclusively solved this conundrum with the demonstration that most nuclear DNA comprises various classes of repeats, primarily transposable eleme...

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Evolutionary active transposable elements in the genome of the coelacanth.

The apparent morphological stasis in the lineage of the coelacanth, which has been called a "living fossil" by many, has been suggested to be causally related to a slow evolution of its genome, with strongly reduced activity of transposable elements (TEs). Analysis of the African coelacanth showed that at least 25% of its genome is constituted of transposable elements including retrotransposons...

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Transposable elements (TEs) are short DNA sequences with the capacity to move between different sites in the genome. This ability provides them with the capacity to mutate the genome in many different ways, from subtle regulatory mutations to gross genomic rearrangements. The potential adaptive significance of TEs was recognized by those involved in their initial discovery although it was hotly...

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ژورنال

عنوان ژورنال: Genome Biology

سال: 2007

ISSN: 1465-6906

DOI: 10.1186/gb-2007-8-s1-s5